机器学习
周丰丰
基本情况
姓名: 周丰丰
性别:
职称: 教授
是否博导:
最高学历: 研究生
最高学位: 博士
Email:
备注: “唐敖庆”教授,中科院“百人计划”。

我的实验室是Health Informatics Lab,简称HILab,欢迎大家访问HILab网站:http://www.healthinformaticslab.org/.
详细情况
所在学科专业: 计算机应用
近期新闻
  • 恭喜HILab软件学院卓越工程师班的四位本科生刘加美、许诚、杨威峰、舒亚芸!她们完成的“算法多解性”成果,被SCI索引的Nature子刊Scientific Reports接收(影响因子:4.2589).
  • 恭喜HILab计算机学院本科生叶玉婷和张若驰,她们完成的“随机重启型特征选择算法”,,被SCI索引的Nature子刊Scientific Reports接收.
所研究方向: 生物信息学,健康大数据挖掘,深度学习,并行计算等
讲授课程: 健康大数据挖掘,机器学习与Python,Python编程等
教育经历:

  • 1996-2000: 中国科学技术大学,少年班学院,计算机软件

  • 2000-2005: 中国科学技术大学,计算机学院,计算机软件

工作经历: 吉林大学唐敖庆教授,博士生导师,中国科学院百人计划,IEEE(美国电气和电子工程师协会)高级会员。周丰丰博士的团队主要从事健康大数据挖掘核心算法的研究。

已发表学术论文31篇,其中包括SCI索引28篇,主要作者论文(通信或者第一作者)21篇。影响因子(IF,下同)合计为104.044分。总引用次数472次,其中他引390次。学术成果多次在包括Nature Protocols(IF: 9.924,1篇)、Nucleic Acids Research(IF: 8.026, 3篇)、Bioinformatics(IF: 5.468,3篇)、BMC Genomics(IF: 4.073, 2篇)和Genetics(IF: 4.007,1篇)等高水平SCI索引学术期刊上发表。相关成果连续荣获国际疾病预测竞赛2012年度第三名(共55个学术团队参加)和2013年度第四名(共28个学术团队参加)。应邀担任新杂志Frontiers in Bioinformatics and Computational Biology的副主编(associate editor,大陆唯一),Interdisciplinary Sciences: Computational Life Sciences(SCI索引,新索引杂志,影响因子正在计算中) 副主编,Computers in Biology and Medicine (SCI索引,影响因子1.089)的编委,PLoS ONE (SCI索引,影响因子4.351)的编委,以及BioEnergy Research(SCI索引,影响因子3.562)的唯一生物信息学编委,并多次(每一类均超过20次)应邀评审国际和国内项目标书、国际学术期刊和会议的投稿论文。

目前已毕业的学生找到的工作机会包括百度和南方信投等大数据挖掘领域的大数据分析师等职位,欢迎有志于从事大数据领域研究和开发的同学申请和报考本实验室的计算机应用专业博士和硕士研究生。。
科研项目: 曾经与正在承担相关项目300万。
学术论文: * 共同第一作者, # 通信作者,标为红色的是近期论文

1. Yuting Ye, Ruochi Zhang, Weiwei Zheng, Shuai Liu, Fengfeng Zhou#. “RIFS: a randomly restarted incremental feature selection algorithm”. Accepted by Scientific Reports.
2. Jiamei Liu, Cheng Xu, Weifeng Yang, Yayun Shu, Weiwei Zheng, Fengfeng Zhou#. “Multiple similarly-well solutions exist for biomedical feature selection and classification problems”. Accepted by Scientific Reports.
3. Ruiquan Ge, Guoqin Mai, R Zhang, X Wu, Q Wu, Fengfeng Zhou#. “MUSTv2: An Improved De Novo Detection Program for Recently Active Miniature Inverted Repeat Transposable Elements (MITEs)”. Accepted by Journal of Integrative Bioinformatics, 2017.
4. Pu Wang, Ruiquan Ge, Xuan Xiao, Yunpeng Cai, Guoqing Wang, Fengfeng Zhou#. “Rectified-Linear-Unit-Based Deep Learning for Biomedical Multi-label Data”. Interdisciplinary Sciences – Computational Life Sciences, 9: 419–422, 2017.
5. Yan Xu, Li Li, Jun Ding, Ling-Yun Wu, Guoqin Mai, Fengfeng Zhou#. “Gly-PseAAC: Identifying protein lysine glycation through sequences”. Gene, 602: 1-7, 2017.
6. Pu Wang, Ruiquan Ge, Xuan Xiao, Manli Zhou, Fengfeng Zhou#. “hMuLab: a Biomedical Hybrid MUlti-LABel Classifier Based on Multiple Linear Regression”. Accepted by IEEE Transactions on Computational Biology and Bioinformatics, 2016.

7. Yu Wang, Yaonan Zhang, Zhaomin Yao, Ruixue Zhao, Fengfeng Zhou#. “Machine learning based detection of age-related macular degeneration (AMD) and diabetic macular edema (DME) from optical coherence tomography (OCT) images”. BioMedical Optics Express, 7 (12): 4928-4940, 2016.
8. Ruiquan Ge, Guoqin Mai, Pu Wang, Manli Zhou, Youxi Luo, Yunpeng Cai, Fengfeng Zhou#. “CRISPRdigger: detecting CRISPRs with better direct repeat annotations”. Scientific Reports, 6: 32942, 2016.
9. Dongli Ma, Shan Zhong, Xiaorong Liu, Huirong Mai, Guoqin Mai, Cheng Xu, Fengfeng Zhou#. “CD3D and PRKCQ work together to discriminate between B-cell and T-cell acute lymphoblastic leukemia”. Computers in Biology and Medicine, 77: 16-22, 2016.
10. Guoqin Mai, Ruiquan Ge, Guoquan Sun, Qinghan Meng, Fengfeng Zhou#. “A comprehensive curation shows the dynamic evolutionary patterns of prokaryotic CRISPRs”. BioMed Research International, 2016: 7237053, 2016.
11. Ruiquan Ge, Manli Zhou, Youxi Luo, Qinghan Meng, Guoqin Mai, Dongli Ma, Guoqing Wang, Fengfeng Zhou#. "McTwo: a two-step feature selection algorithm based on maximal information coefficient ". BMC Bioinformatics 17: 142, 2016.
12. Miaomiao Zhao, Yunpeng Cai, Jiankui He, Guanyu Wang, Dongqing Wei, Yanjie Wei, Caiwan Zhang, Fengfeng Zhou#. “Personalized clinical data screening: Special issue on health informatics”. Computers in Biology and Medicine, 61: 161-162, 2015.
13. Bin Liu, Jikui Liu, Guoqing Wang, Fan Li, Yang Zheng, Fengfeng Zhou#. "A Novel Electrocardiogram Parameterization Algorithm and its Application in Myocardial Infarction Detection". Computers in Biology and Medicine 61: 178-184, 2015.
14. Miaomiao Zhao, Zhao Zhang, Guoqin Mai, Youxi Luo, Fengfeng Zhou#. "jEcho: an Evolved weight vector to CHaracterize the protein's post-translational modification mOtifs". Interdisciplinary Sciences: Computational Life Sciences, 7:194-199, 2015.
15. Wei Du, Zhongbo Cao, Yan Wang, Fengfeng Zhou, Wei Pang, Xin Chen, Yuan Tian, Yanchun Liang. “Specific Biomarkers: Detection of Cancer Biomarkers Through High-Throughput Transcriptomics Data”. Cognitive Computation 7 (6), 652-666, 2015.
16. Manli Zhou*, Youxi Luo*, Guoquan Sun, Guoqin Mai, Fengfeng Zhou#. "Constraint Programming based Biomarker Optimization". BioMed Research International, 910515, 2015.
17. Zhao Zhang*, Miaomiao Zhao*, Guoqin Mai, Youxi Luo, Ze Wang, Fengfeng Zhou#. "Evolutionary optimization of transcription factor binding motif detection". Advances in Experimental Medicine and Biology, 827: 261-274, 2015.
18. Jiao Xie, Fengfeng Zhou, Guangyu Xu, Guoqin Mai, Jie Hu, Guoqing Wang, Fan Li. “Genome-wide screening of pathogenicity islands in Mycobacterium tuberculosis based on the genomic barcode visualization”. Molecular Biology Reports 41(9):5883-5889, 2014.
19. Weihua Pan, Yanan Zhao, Yun Xu# and Fengfeng Zhou#. "WinHAP2: an extremely fast haplotype phasing program for long genotype sequences". BMC Bioinformatics 15(1):164, 2014.
20. Bin Liu, Xiaotian Zhang, Honglan Huang, Ying Zhang, Fengfeng Zhou#, Guoqing Wang#. "A novel molecular typing method of Mycobacteria based on DNA barcoding visualization". Journal of Clinical Bioinformatics 4 (1), 4, 2014.
21. Pi Guo*, Youxi Luo*, Guoqin Mai, Ming Zhang, Guoqing Wang#, Miaomiao Zhao, Liming Gao, Fan Li, Fengfeng Zhou#. "Gene Expression Profile based Classification Models of Psoriasis". Genomics, 103 (1), 48-55, 2014.
22. Adi L. Tarca, Mario Lauria, Michael Unger, Erhan Bilal, Stephanie Boue, Kushal Kumar Dey, Julia Hoeng, Heinz Koeppl, Florian Martin, Pablo Meyer, Preetam Nandy, Raquel Norel, Manuel Peitsch, Jeremy J. Rice, Roberto Romero, Gustavo Stolovitzky, Marja Talikka, Yang Xiang, Christoph Zechner and IMPROVER DSC Collaborators. "Strengths and limitations of microarray-based phenotype prediction: lessons learned from the IMPROVER Diagnostic Signature Challenge". Bioinformatics 29(22), 2892-2899, 2013.
23. Meixue Yang, Bin Liu, Fan Li, Guoqing Wang#, Fengfeng Zhou#. "Normalizing electrocardiograms of both healthy persons and cardiovascular disease patients for biometric authentication". PLoS ONE, 8 (8), e71523, 2013.
24. Qilin Ma, Youxi Luo, Pi Guo, Gan Gao, Meixue Yang, Fengfeng Zhou#. “Clinical effects of Xinmailong therapy in patients with chronic heart failure”. International Journal of Medical Sciences, 10(5):624-633, 2013.
25. Gaurav Sablok, XianMing Wu, Kinshuk Chandra Nayak, Jimmy Kuo, Vesselin Baev, Fengfeng Zhou. “Combinational effect of mutational bias and translational selection for translation efficiency in tomato (Solanum lycopersicum) cv. Micro-Tom”. Genomics, 101(5):290-295, 2013.
26. Kaishi Li, Meixue Yang, Gaurav Sablok, Jianping Fan#, Fengfeng Zhou#. “Screening features to improve the class prediction of acute myeloid leukemia and myelodysplastic syndrome”, Gene, 512:348-354, 2013.
27. Yun Xu#, Wenhua Cheng, Pengyu Nie, Fengfeng Zhou#. “WinHAP: an Efficient Haplotype Phasing Algorithm based on Scalable Sliding Windows”. PLoS ONE, 7(8):e43163, 2012.
28. Fengfeng Zhou*, Qin Ma*, Guojun Li, Ying Xu. “QServer: A Biclustering Server for Prediction and Assessment of Co-Expressed Gene Clusters”, PLoS ONE 7(3):e32660, 2012.
29. Guoqing Wang, Fengfeng Zhou, Victor Olman, Yingying Su, Ying Xu, Fan Li, “Computational prediction and experimental validation of novel markers for detection of STEC O157:H7”, World Journal of Gastroenterology, 17(14):1910-1914, 2011.
30. Phuongan Dam, Irina Kataeva, Sung-Jae Yang, Fengfeng Zhou, Yanbin Yin, Wenchi Chou, Farris L., Poole II, Janet Westpheling, Robert Hettich, Richard Giannone, Derrick L. Lewis, Robert Kelly, Harry J. Gilbert, Bernard Henrissat, Ying Xu and Michael W.W. Adams, "Insights into Plant Biomass Conversion from the Genome of the Anaerobic Thermophilic Bacterium Caldicellulosiruptor bescii DSM 6725", Nucleic Acids Research, 2011 39(8):3240-3254.
31. Fengfeng Zhou, Ying Xu, “cBar: a computer program to distinguish plasmid-derived from chromosome-derived sequence fragments in metagenomics data”, Bioinformatics 2010 26: 2051-2052.
32. Guoqing Wang, Fengfeng Zhou, Victor Olman, Fan Li, Ying Xu, “Prediction of pathogenicity islands in enterohemorrhagic Escherichia coli O157:H7 using genomic barcodes”, FEBS Letters 2010 584(1):194-198.
33. Fengfeng Zhou, Huiling Chen, Ying Xu, "GASdb: a large-scale and comparative exploration database of glycosyl hydrolysis systems", BMC Microbiology 2010 10:69.
34. Fengfeng Zhou and Ying Xu, "Large scale analyses of glycosylation in cellulases", Genomics, Proteomics & Bioinformatics 2009 7(4):194-199.
35. Fenglou Mao, Yanbin Yin, Fengfeng Zhou, Wen-Chi Chou, Chan Zhou, Huiling Chen, Ying Xu, "pDAWG: An Integrated Database for Plant Cell Wall Genes", BioEnergy Research 2009 2(4):209-216.
36. Thao Tran, Fengfeng Zhou, Sarah Marshburn, Mark Stead, Sidney Kushner, and Ying Xu, "De novo computational prediction of non-coding RNA genes in prokaryotic genomes", Bioinformatics 2009 25(22):2897-2905.
37. Irina A Kataeva, Sung-Jae Yang, Phuongan Dam, Farris L Poole II, Yanbin Yin, Fengfeng Zhou, Wen-chi Chou, Ying Xu, Lynne Goodwin, David R Sims, John C Detter, Loren J Hausser, Janet Westpheling and Michael WW Adams, " Genome Sequence of the Anaerobic, Thermophilic, and Cellulolytic Bacterium "Anaerocellum thermophilum" DSM 6725", Journal of Bacteriology 2009 191:3760-3761.
38. Yong Chen*, Fengfeng Zhou*, Guojun Li, and Ying Xu, " MUST: A system for identification of miniature inverted-repeat transposable elements and applications to Anabaena variabilis and Haloquadratum walsbyi", Gene 2009 436:1-7.
39. Bin Liu, Fengfeng Zhou, Suijie Wu, Ying Xu and Xiaobo Zhang, "Genomic and Proteomic Characterization of a Thermophilic Geobacillus Bacteriophage GBSV1", Research in Microbiology 2009 160:166-171.
40. Chan Zhou, Fengfeng Zhou, Ying Xu, "Comparative analyses of distributions and functions of Z-DNA in Arabidopsis and rice", Genomics 2009 93:383-391.
41. Fengfeng Zhou, Ying Xu, “RepPop: a database for repetitive elements in Populus trichocarpa”, BMC Genomics 2009 10:14.
42. Fengfeng Zhou*, Victor Olman*, Ying Xu, “Barcodes for Genomes and Applications”, BMC Bioinformatics 2008 9:546.
43. Yong Chen*, Fengfeng Zhou*, Guojun Li, and Ying Xu, "A recently active miniature inverted-repeat transposable element, Chunjie, inserted into an operon without disturbing the operon structure in Geobacter uraniireducens Rf4", Genetics 2008 179: 2291-2297.
44. Fengfeng Zhou, Victor Olman, Ying Xu, "Insertion Sequences show diverse recent activities in Cyanobacteria and Archaea", BMC Genomics, 2008 9:36.
45. Fengfeng Zhou, Thao Tran, Ying Xu, "Nezha, a novel active miniature inverted-repeat transposable element in cyanobacteria", Biochemical and Biophysical Research Communications 2008 365(4):790-794.
46. Fengfeng Zhou*, Yu Xue*, Xuebiao Yao, Ying Xu, "A general user interface for prediction servers of proteins'; post-translational modification sites ", Nature Protocols 2006 1(3):1318-1321.
47. Yu Xue*, Fengfeng Zhou*, Chuanhai Fu, Ying Xu, Xuebiao Yao, "SUMOsp: a web server for sumoylation site prediction", Nucleic Acids Research 2006 34:W254-W257.
48. Fengfeng Zhou*, Yu Xue*, Xuebiao Yao, Ying Xu, "CSS-Palm: Palmitoylation Site Prediction with a Clustering and Scoring Strategy (CSS)", Bioinformatics 2006 22(7):894-896.
49. Fengfeng Zhou*, Yu Xue*, Hualei Lu, Guoliang Chen, Xuebiao Yao, "A genome-wide analysis of sumoylation-related biological processes and functions in human nucleus", FEBS Letters 2005 579: 3369-3375.
50. Yu Xue*, Fengfeng Zhou*, Minjie Zhu, Kashif Ahmed, Guoliang Chen, Xuebiao Yao, "GPS: A comprehensive www server for phosphorylation sites prediction", Nucleic Acids Research 2005 33: W184-W187.
51. Zuozhou Chen, Chenghai Xue, Sheng Zhu, Fengfeng Zhou, Xuefeng Bruce Ling, Guoping Liu, Liangbiao Chen, "GoPipe: Streamlined Gene Ontology Annotation for Batch Anonymous Sequences with Statistics", Progress in Biochemistry and Biophysics 2005 32:187-191.
52. Fengfeng Zhou, Yinlong Xu, Guoliang Chen, "No-wait Scheduling in Single-hop Multi-channel LANs", Information Processing Letters 2005 93:19-24.
53. Fengfeng Zhou*, Yu Xue*, Guoliang Chen, Xuebiao Yao, "GPS: A Novel Group-based Phosphorylation Predicting and Scoring Method", Biochemical and Biophysical Research Communications 2004 325:1443-1448.
54. Fengfeng Zhou, Guoliang Chen, Yinlong Xu, J. Gu, "Minimizing ADMs on WDM Directed Fiber Trees", J. Comput. Sci. & Technol. 2003 18(6):725-731.
获奖情况: 1. 2016: Rank 4th, “Systems Toxicology Computational Challenge”, sbv IMPROVER competition 2016, Advisor of the team HILab.
2. 2015年:“中国好创意”全国青年大数据创新大赛(国家互联网信息办公室网络数据与技术局、中国计算机学会),“基于大数据的未知病原检测方法构建”赛题,二等奖,HI-15MW代表队,指导老师。
3. 2014年:第二届中国大数据技术创新大赛(中国计算机学会大数据专家委员会),HILab_SIAT代表队,成功参与奖,指导老师。
4. 2013年:疾病预警建模算法NetTrans荣获2013年度国际IMPROVER疾病预警建模竞赛第四名(共28个国际团队参加)。颁奖及学术交流会议,希腊雅典,2013年10月29-31日。
5. 2013年:深圳市海外高层次人才“孔雀计划”B类人才。
6. 2012年:疾病预警建模算法cPsoriasis荣获2012年度国际IMPROVER疾病预警建模竞赛-自免疫疾病第三名(共55个国际团队参加)。颁奖及学术交流会议,美国波士顿,2012年10月2-3日。
社会兼职: 1. 委员(2016-现在,首批委员),中国计算机学会生物信息学专业组,2016年-现在。
2. 委员(2016-现在),中国计算机学会计算机应用专业委员会,2016年-现在。
3. 通讯委员(2016-现在),中国计算机学会大数据专业委员会,2016年-现在。
4. 高级会员(2016年-现在),会员(2013-2016),中国计算机学会,2016-现在。
5. 终身会员(2013-现在),中国运筹学会,2013-现在。
6. 高级会员(2013-现在),会员(2012-2013),IEEE。
治学格言: 鼓励探索、严谨治学。

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